Pragyandip Dash, Anuradha Mishra, Amit K Chaturvedi and Devdutt Chaturvedi
In this study, we determined the antiulcer effect of Haldina cordifolia in NSAID-induced rats. The methanolic extract was administered orally at 100 mg/kg and 50 mg/kg of body weight at 8-hour intervals. Diclofenac sodium was used as the ulcer-inducing agent. The result was satisfactory as there was a marked improvement in the ulcerated part. The extract was able to decrease acid secretion in the stomach and increase mucosal damage.
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