Kinthali Usha Rani, Shaheen Begum
Background: A cereal is a grass cultivated for its edible grain components, a source of food, nutraceuticals, and pharmaceutical components.
Objective: The aim of the present study was to explore the pharmacological, phytochemical, pharmaceutical, nutraceutical, preclinical and clinical profile of Avena sativa L.
Materials and Methods: Different databases like PubMed, Scopus, Google Scholar and Science Direct were searched for research articles to document different pharmacological and phytopharmaceutical applications of Avena sativa; this review creates evidence for its scientific basis. The bioactive molecules of Avena sativa include aventramide, tocols, β-glucan, lignans, anthocyanidins, β-glucan, arabinoxylans and other polysaccharides. The reported clinical data suggest that regular consumption of oats is likely to reduce health risks like cardiovascular diseases, chronic obstructive pulmonary disease and health problems related to the gastrointestinal tract.
Conclusion: Review of all clinical results indicates that Avena sativa is a potential candidate as a nutraceutical and pharmaceutical agent. The advantages were observed in clinical studies, but it would be advisable to test it in larger studies for further exploration within the therapeutic aspect.