Abstracto

Synthesis and Evaluation of Novel 1, 5- Benzothiazepine Derivatives as Anti- Inflammatory Agents

Ganesh R. Mhaske, ShivdasS. Bajod, DamodharM. Ambhore and Sharad N. Shelke

Novel 1, 5-benzothiazepine derivatives were synthesized and characterized by spectral studies. The newly synthesized compounds (4a–g) were screened for in vivo anti-inflammatory activity at a dose of 10 mg/kg BW. Among those tested, compounds 4c, 4d and 4g exhibited significant anti-inflammatory activity in models of acute inflammation such as rat paw edema, while compounds 4c and 4g showed considerable activity compared with diclofenac as a standard drug.

Descargo de responsabilidad: este resumen se tradujo utilizando herramientas de inteligencia artificial y aún no ha sido revisado ni verificado.

Indexado en

Academic Keys
ResearchBible
CiteFactor
Cosmos SI
Búsqueda de referencia
Universidad Hamdard
Catálogo mundial de revistas científicas
director académico
Factor de impacto de revistas innovadoras internacionales (IIJIF)
Instituto Internacional de Investigación Organizada (I2OR)
Cosmos

Ver más