Pushpa Agrawal , Karan Mehta , Pooja Vashisth , Sudarshan , Preethi Bhat B V Goutham Vishnu
Modern dental restoration materials fulfil all the physical, biocompatibility and aesthetics requirements but they do not possess antibacterial activity to protect the tooth from recurrent caries. In this direction, many researchers worked on incorporation of different antibacterial agents like silver, antibiotics, Zinc oxide etc, in dental filling materials. The objective of present research work was to conduct the green synthesis of silver nanoparticles using Azadirachta indica extract and to incorporate these into dental filling material to confer antibacterial activity to the dental filling material. In order to fulfil the objective of this work, various experimental parameters of the process of green synthesis of silver nanoparticles were optimized. The SNPs were then characterized using UV-Vis spectrophotometer, particle size analyser, FTIR spectrophotometer. Their antibacterial activity was confirmed using agar diffusion test against E.coli and S.mutans. The silver nanoparticles were then incorporated into Glass Ionomer Cement (Fuji II) and the antimicrobial test conducted using S.mutans and the results indicated the increase antimicrobial property. The novel material is not soluble in the common beverages like tea, coffee, coca cola and lime juice