Muhammad Zubair Khan
Background: Rhizosphere is site of highly production of secondary metabolites by microbes that play key role in pharmacy and agriculture. The Plant Growth Promoting Rhizobacteria (PGPRs) are the most abundant organisms of rhizosphere that comprise a broad range of biological activities. Biotechnology approach researches of the rhizosphere have had helped enormously with management of diseases prevention and enhancing livelihood of both humans and plants.
Scope: The diverse natural bioactivities secondary metabolites of PGPR Bacillus genera possess antibacterial, antifungal, anticancer and insecticidal activities. These activities prevent the pathogenicity in soil and indirectly promote plant growth. These natural products are precious commodity in pharmaceutical, drug discovery and drug design.
Conclusion: This review highlights generally PGPR Bacillus spp.; particularly B. subtilis role in pharmaceutical and agriculture field.
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