Abstracto

Clinical Profile and Outcome of Mechanically Ventilated Children in Pediatric Intensive Care Unit of a Tertiary Hospital: Retrospective Analysis

 Mehretie Kokeb*, Mulualem Biazen

Background: Studies on Mechanical ventilation and its outcome in children are very few in African pediatric intensive care units. Understanding the outcome of children with mechanical ventilation is very crucial. Our aim was to assess the profiles and outcomes of mechanically ventilated pediatric patients aged 1 month-18 years at the University of Gondar Hospital (UoGH), pediatric intensive care unit. Methods: A retrospective review of medical records of Children (1 month-18 years) admitted to the university of Gondar hospital, PICU from June 1st, 2015 to September 30th, 2021 was conducted. Both descriptive and analytical statistical methods were applied and logistic regression analyses were carried out to determine the factors on outcome of mechanically ventilated children. Results: There were a total of 115 mechanically ventilated children during the study period. Sixty eight (59.1%) participants were males and 63 (54.8%) mechanically ventilated children died. The major indications for the initiation of ventilation were neurologic complications which occurred in 49 (42.6%) children and respiratory conditions which contributed for 48 (41.7%) children. severe malnutrition (AOR=0.09, 95% CI (0. 02, 0.47), night time extubation (AOR=0.06, 95% CI (0.01, 0.58) and those who stayed less than 3 days in PICU (AOR=20.60, 95% CI (1.54, 27.86) were found to have higher mortality rate (p<0.01). Conclusion: The mortality rate of mechanically ventilated children was 54.8%. Major contributors for death were malnutrition, night time extubation and short stay.